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Jaeger,
Christine B., Ph.D.
Associate Professor of Anatomy
BA ‘75, University of Iowa; PhD ‘79, University
of Washington
E-mail:cbj@vet.purdue.edu
Research Interests:
Development, plasticity and regeneration
of the central nervous system (CNS) after trauma. Homeostasis
of the neuronal environment, required for function, is dynamically
controlled by cell interactions of neurons and non-neurons.
These cell interactions are grossly disturbed following a
CNS injury. A goal of my research is to identify alternative
sources for neuron replacement therapies and define the role
of specific cell interactions in CNS repair processes.
Publications
Jaeger, C.B. and Blight,
A.R. (1997) Spinal Cord Compression Injury in Guinea Pigs:
Structural Changes of Endothelium and Its Perivascular Cell
Associations after Blood-Brain Barrier Breakdown and Repair.
Experimental Neurology 144:381-399.
Jaeger, C.B. (1995) Isolation
of enteric ganglia from the myenteric plexus of adult rats.
J. Neural Transpl. Plasticity, 5:223-232
Borgens, R.B., Shi, R., Mohr, T.J. and Jaeger,
C.B. (1994) Mammalian cortical astrocytes align themselves
in a physiological voltage gradient. Exp. Neurol., 128:41-49.
Jaeger, C.B., Toombs, J.P.
and Borgens, R.B. (1993) Grafting in acute Spinal Cord Injury:
Morphological and immunological aspects of transplanted adult
rat enteric ganglia. Neurosci., 52:333-346.
Jaeger, C.B., Aebischer,
P, Tresco, P.A., Winn, S.R. and Greene, L.A. (1992) Growth
of tumor cell lines in macrocapsules: Ultrastructure of encapsulated
PC12 cells. J. Neurocytol., 21:469-480.
Tresco, P.A., Winn, S.R., Jaeger,
C.B., Greene, L.A., and Aebischer, P. (1992) Transplantation
of polymer encapsulated PC12 cells reduces lesion-induced
rotational behavior. Cell Transplantation, 1:255-264.
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