Education

Overview of Research

Veterinary Pathobiology
    Toxicopathology, cardiovascular and respiratory pathology; swine models of human diseases; diagnostic pathology.

Publications

Refereed journals

Anderson TD, Van Alstine WG, Miskimins DW, Ficken MD, Osweiler GD, Carson TL: Acute monensin toxicosis in sheep: Light and electron microscopic changes. Am J Vet Res 45(6):1142-1147, 1984.

Van Alstine WG, Anderson TD, Reed DE, Wheeler BA: Vaccine- induced pseudorabies in lambs. J Am Vet Med Assoc 185(4):409-410, 1984.

Van Alstine WG, Trampel DW: Polycystic kidneys in a pigeon. Avian Dis. 28(3):758-764, 1984.

Drager DD, Van Alstine WG: Dermatophilus infection in an Iowa dairy herd. Iowa State University Veterinarian 47(1):56-58, 1985.

Van Alstine WG, Cook WO, Carson TL: Carbon monoxide-induced fetal death in swine. Vet Med 80(1):88-90, 1985.

Van Alstine WG, Daniels GN: A simple flotation technique to detect sarcoptic mange mites in swine. Vet Med 80(1):88-90, 1985.

Van Alstine WG, Dyer DC: Antibiotic aerosolization: Tissue and plasma oxytetracycline concentrations in turkey poults. Avian Dis. 29(2):430-436, 1985.

Van Alstine WG, Hofstad MS: Antibiotic aerosolization: The effect on experimentally induced Alcaligenes rhinotracheitis in turkeys. Avian Dis. 29(1):159-176, 1985.

Brown BS, Van Alstine WG: Infectious laryngotracheitis in a backyard chicken flock. Iowa State University Veterinarian 48(1):36-39, 1986.

Needham D, Van Alstine WG: Respiratory pseudorabies in swine: A review of eighteen cases. Iowa State University Veterinarian 48(2):103-106, 1986.

Dyer DD, Van Alstine WG: Antibiotic aerosolization: Tissue and plasma oxytetracycline concentrations in parakeets. Avian Dis. 31(3):677-679, 1987.

Van Alstine WG, Arp LH: Effects of Bordetella avium infection on the pulmonary clearance of Escherichia coli in turkeys. Am J Vet Res 48(6):922-926, 1987.

Van Alstine WG, Arp LH: Histologic evaluation of lung and bronchus- associated lymphoid tissue in young turkeys infected with Bordetella avium. Am J Vet Res 49(6):835-839, 1988.

Van Alstine WG, Arp LH: Influence of Bordetella avium infection on association of Escherichia coli with turkey trachea. Am J Vet Res, 48(11):1574-1576, 1987.

Van Alstine WG, Arp LH: Quantitative reduction of 2,3,4-triphenyl tetrazolium chloride by turkey tracheal organ cultures: Effects of Bordetella avium toxins. Avian Dis 31(1):136-139, 1987.

Van Alstine WG, Schwartz KJ, Miskimins DW: Cytology as a diagnostic aid in swine practice, part I. Comp for Cont Educ 9:(6):F225-F228, 1987.

Van Alstine WG, Schwartz KJ, Miskimins DW, Andrews JJ: Cytology as a diagnostic aid in swine practice, part II. Comp for Cont Educ 9(7):F243- F248, 1987.

Van Alstine WG, Dietrich JA: Porcine sciatic nerve damage after intramuscular injection. Comp on Cont Educ 10(11): 1329-1332, 1988.

Koob MD, Van Alstine WG: Blood collection in pet birds, raptors, waterfowl, and poultry. Part I. Mod Vet Pract 2:68-70, 1988.

Koob MD, Van Alstine WG: Blood collection in pet birds, raptors, waterfowl, and poultry. Part II. Mod Vet Pract 3:131-134, 1988.

Cook WD, Van Alstine WG, Osweiler GD: Aflatoxicosis in Iowa swine: Eight cases (1983-1985). J Am Vet Med Assoc 194(4):554-558, 1989.

Jack SW, Van Alstine WG, Swackhamer J: Besnoitiasis in Indiana opossums. J Vet Diag Investig 1(2):189-191, 1989.

Van Alstine WG, Toben CG: Detachment of the tuber ischiadicum in swine. Comp on Cont Educ 11(7):874-879, 1989.

Wolf DC, Van Alstine WG: Osteopetrosis in five fetuses from a single herd of 16 cows. J Vet Diag Investig 1(3):262-264, 1989.

Fitzgerald SD, Van Alstine WG: Diagnosing the underlying cause of end-stage kidney Disease in a Shar Pei Puppy. Vet Med 85 (4): 332-338, 1990.

Sojka JE, White MR, Widmer WR, Van Alstine WG: An unusual case of traumatic pericarditis in a cow. J Vet Diag Invest 2: 139-142, 1990.

Murphy DM, Van Alstine WG, Bowersock T.: Binding of a recombinant form of streptococcal protein G to porcine IgG. J Vet Diag Invest 4(4):469-470, 1992.

Plumlee K, Van Alstine WG: Japanese Pieris intoxication in a goat. J Vet Diag Invest 4(3):363-364, 1992.

Clark LK, Armstrong CH, Scheidt AB, Van Alstine WG: The effect of Mycoplasma hyopneumoniae infection either alone or in combination with environmental constraints on growth in pigs. J Swine Health and Prod 1(6):10-14, 1993.

Diekman MA, Scheidt AB, Sutton AL, Green ML, Clapper JA, Kelly DT, Van Alstine WG: Growth and reproductive performance of gilts infected naturally with pneumonia and atrophic rhinitis during exposure to ammonia. Am J Vet Res 54(12):2128-2131, 1993.

Freed M, Clark JP, Bowersock TL, Van Alstine WG, Balog JM, Hester PY: The effect of spectinomycin in treating colibacillosis in ducklings. Avian Dis 37(3):763-766, 1993.

Murphy DM, Van Alstine WG, Clark LK, Albreghts SR, Knox KE: Aerosol vaccination of pigs against Mycoplasma hyopneumoniae infection. Am J Vet Res 54(11):1874-1880, 1993.

Stevenson GW, Van Alstine WG, Kanitz CL, Keefaber K: Endemic PRRS virus infection of nursery pigs in two swine herds without current reproductive failure. J Vet Diag Invest 5:432-434, 1993.

Van Alstine WG, Kanitz CL, Stevenson GW: Time and temperature survivability of PRRS virus in serum and tissue in experimentally infected piglets. J Vet Diag Invest 5:621-622, 1993.

Van Alstine WG, Stevenson GW, Kanitz CL: Diagnosis of PRRS. J Swine Health and Production. 1:24-28, 1993.

Van Alstine WG, Wickliffe L, Everson RE, DeNicola DB: Lead toxicosis in a household of cats. J Vet Diag Invest 5:496-498, 1993.

Amass SR, Clark LK, Van Alstine WG: Interactions of infection and immunity of Mycoplasma hyopneumoniae and Pasteurella multocida in swine. Am J Vet Res 204(1):102-107, 1994.

Clark LK, Hill MA, Kniffen TS, Van Alstine WG, et al.: An evaluation of medicated early weaning procedures. J. Swine Health and Production. 2(3):5-11, 1994.

Hooper CC, Van Alstine WG, Stevenson GW, Kanitz CL: Mice and rats (laboratory and feral) are not a reservoir for PRRS virus. J Vet Diag Invest 6:13-15, 1994.

Scheidt AB, Mayrose VB, Van Alstine WG, Clark LK, et.al.: The benefit to cost ratio of vaccinating pigs for mycoplasmal pneumonia in a swine herd affected by enzootic pneumonia. J. Swine Health and Production 2(1):7-11, 1994.

Stevenson GW, Van Alstine WG, Kanitz CL: Characterization of endemic PRRS virus infection in a swine herd. J Am Vet Med Assoc 204(12):1938-1942, 1994.

Turek JJ, Schoenlein IA, Clark LK, Van Alstine WG: Dietary polyunsaturated fatty acid effects on immune cells of the porcine lung. J Leukoc Biol 56(5):599-604, 1994.

Scheidt AB, Cline TR, Clark LK, Mayrose VB, Van Alstine WG, et.al.: The effect of all in/all out growing-finishing on the health of pigs. J Swine Health and Production. 3(5):202-205, 1995.

Rudman DG, Van Alstine WG, Doddy FD; et.al.: Pulmonary and mediastinal metastases of a vaccine-site sarcoma in a cat. Vet Pathol 33:466-469, 1996.

Van Alstine WG, Stevenson GW, Kanitz CL: Coinoculation with PRRS virus and Mycoplasma hyopneumoniae in young pigs. J Vet Microbiol 49:297-303, 1996.

Turek JJ, Schoenlein IA, Watkins BA, Van Alstine WG, Clark LK, Knox K: Dietary polyunsaturated fatty acids modulate responses of pigs to Mycoplasma hyopneumoniae infection. J of Nutrition. 126:1541-1548, 1996.

Macri NM, Van Alstine WG, et. al.: Canine spinal nephroblastoma. J Am An Hosp Assoc 33:302-306, 1997.

Brunner JM, Steinger JM, Williams DA, Van Alstine WG, et.al.: Elevated feline trypsin-like immunoreactivity (fTLI) in a cat with pancreatitis and hepatic lipidosis. J Am Vet Med Assoc 210(12):1757-1760, 1997.

Kiupel M, Van Alstine WG, Ritmeester A: Small intestinal adenocarcinoma in a horse. European J of Vet Path 4(1):1-4, 1997.

Siems JJ, Jakovljevic S, Van Alstine WG: Radiographic diagnosis – lung lobe torsion. Vet Radiology and Ultrasound 39:418-420, 1998.

Jakovljevic S, Van Alstine WG, Adams L: Ureteral pseudodiverticulosis in 2 dogs. Vet Radiology and Ultrasound 39(5):425 – 429, 1998.

Irigoyen LF, Van Alstine WG, Turek JJ, Clark LK: Ultrastructural observation of the airways of recovered and susceptible pigs after inoculation with Mycoplasma hyopneumonia. Pesq Vet Bras 18(1): 1-7, 1998.

Clark LK, Wu CC, Van Alstine WG, Knox K: Evaluation of the effectiveness of a macrolide antibiotic on reduction of respiratory pathogens in 12 day and 21 day weaned pigs. J Swine Health and Production. 6(6):257-262, 1998.

Kiupel M, Van Alstine WG, Kilbane T, Albers J: Clinical Challenge – case 2. Cholelithiasis in a large-toothed rock hyrax. J Zoo and Wildlife Med 30(1):177-178, 1999.

Hooser SB, Van Alstine WG, Kiupel M, Sojka JE: Acute pit gas (Hydrogen Sulfide) poisoning in confinement cattle. J Vet Diag Invest 12(3):272-275, 2000.

Escobar J, Van Alstine WG, Baker DH, Johnson RW: Growth performance and whole body composition of pigs experimentally inoculated with Mycoplasma hyopneumoniae. J Animal Sci 80(2): 384-391, 2002.

Van Alstine WG, Popielarcyzk M, Albregts SR: Effect of formalin fixation on the immunohistochemical detection of PRRS virus antigen in experimentally and naturally infected pigs. J Vet Diagn Invest 14(6), 504-507, 2002.

Toyota N, Pavcnik D, Van Alstine WG, et.al: Experimental Comparison of SIS Covered-and noncovered nitinol stents: A pilot study in the sheep iliac arteries. J Vasc Interventional Radiology 13: 489-498, 2002.

Hogan D, Green HW, Van Alstine WG: Total Anomalous pulmonary venous drainage in a puppy. J Vet Internal Med 16(3): 303-308, 2002.

VanAlstine WG, Widmer WR: Lightning injury in an outdoor swine herd. J Vet Diag Invest 15:289-291, 2003.

Kuipel M, Van Alstine WG, Chilcoat C: Gross and microscopic lesions of polioencephalomalacia in a llama. J Zoo Wildlife Dis 34(3):309-311, 2003.

Manabu N, Pavcnik D, Van Alstine WG, Uchida B, et.al.: Comparison of SIS covered and noncovered nitinol stents with PTFE endografts in ovine femoral arteries – a pilot study. Cardiovasc Intervent Radiol 26(5):459-467, 2003.

Escobar J, Van Alstine WG, Baker DH, Johnson RW: Decreased protein accretion in pigs with viral and bacterial pneumonia is associated with increased myostatin expression in muscle. J Nutr 134:3047-3053, 2004.

Toepfer-Berg TL, Escobar J, Van Alstine WG, et al.: Vitamin E supplementation does not mitigate the acute morbidity effects of PRRSV in nursery pigs. J An Sci 82:1942-1951, 2004.

Boulineau TM, Andrews-Jones L, Van Alstine WG: Spontaneous aortic dissection in two Border Collies. J Vet Diagn Invest 17:492-497, 2005.

Ruiz CE, Iemura M, Medie S, Varga P, Van Alstine WG, et al. Transcather placement of a low-profile pulmonary valve made of SIS: A long term study in a swine model. J Thoracic Cardiovas Surg, 130(2):477-484, 2005.

Schoeniger S, Van Alstine WG, Donner LR: Malignant ocular medulloepithelioma in a llama (Llama glama). J Vet Diagn Invest 18:499-503, 2006.

Beier UH, Mack S, Doran JL, Van Alstine WG, Ruiz CE: Small intestinal submucosa prosthetic percutaneous valve: Reduction in leaflet thickening with low-profile self-centering valve frame. Euro Intervention, Suppl. A53-A59, 2006.

Escobar J, Van Alstine WG, Baker DH, Johnson RW: Behaviour of pigs with viral and bacterial pneumonia. Accepted for publication, Applied An Behaviour Sci, 2006.