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Infectious Diseases and Inflammation Research

The immune system of human beings and domestic animals has evolved to protect the body from microbial infections. Vaccination is aimed at mobilizing the immune defense mechanisms and is one of the most successful medical interventions. It has led to the eradication of small pox in people and rinderpest in cattle, and almost complete eradication of polio. Yet, infectious diseases continue to plague human and animal populations. The majority of emerging infectious diseases that affect human beings originate in animals emphasizing the need to control infections in both domestic animals and wildlife populations.

Research in the College of Veterinary Medicine is aimed at the control of infectious diseases that affect humans and animals through improved diagnostics, therapeutics and vaccination. Some of the work includes the development of new diagnostic tests for infectious diseases; development of new antibiotics against SalmonellaListeria and MRSA; recombinant adenoviral vectors for effective influenza vaccines; the study of influenza and other viral diseases in poultry and swine; and epidemiologic studies of zoonotic infectious diseases.

While the immune system is necessary for the defense against infections, abnormal functioning of the immune system can cause life-threatening and debilitating diseases often associated with chronic inflammation. Such diseases affect both humans and domestic animals, and research in the College of Veterinary Medicine is aimed at the development of novel therapies. Examples of diseases that are being investigated include inflammatory bowel disease, chronic dermatitis, prostatitis, and allergic airway disease in horses.

Faculty

Infectious Diseases:

Diagnostics

Epidemiology

Pathogenesis

Therapeutics

Vaccines

Inflammation:

Diagnostics