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Clinical Investigations
Canine Bladder Cancer Treatment of Canine Bladder Cancer (Transitional cell carcinoma, "TCC")
A new chemotherapy protocol is being evaluated for dogs with transitional cell carcinoma of the urinary bladder. The study will compare the chemotherapy by itself vs. that chemotherapy combined with an NSAID. A diagnosis via tissue biopsy is required.
Imaging Bladder Cancer
Causes of Bladder Cancer In conjunction with the Ostrander Lab at NIH, we are studying the DNA of dogs with TCC with the goal of discovering factors causing genetic predisposition for this disease. A very small amount of blood is requested from Scottish Terriers, West Highland White Terriers and Shetland Sheepdogs over 5 years old and have confirmed (via biopsy)TCC.
Learning More About TCC Tissue samples at the time of euthanasia of any dog or cat with TCC would be valuable. Snap frozen or formalin-fixed tissues of the urinary bladder tumor, regional lymph nodes, liver, and any other suspected site of tumor spread are requested.
Because certain cancers in dogs and humans take up the vitamin, folate, Purdue researchers are investigating a folate/chemotherapy conjugate as a way of selectively delivering therapy to the tumor.
Influence of Prednisone on Remission and P-glycoprotein expression in Dogs with Lymphoma
Canine Osteosarcoma A new treatment protocol is being evaluated post amputation with a diagnosis of osteosarcoma.
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