Purdue University

Purdue University

School of Veterinary Medicine
Veterinary Clinical Sciences

ABSTRACT

Response to High-dose Radioactive Iodine Administration in Cats with Thyroid Carcinoma that had Previously Undergone Surgery

L. Guptill, MS, DVM; JCR Scott-Moncrieff, MA, VetMB, MS; WE Blevins, DVM, MS (From the Dept. of Veterinary Clinical Sciences, Purdue University); EB Janovitz, DVM, PhD; DB DeNicola, DVM, PhD (From the Department of Veterinary Pathobiology, Purdue University); SE Yohn, DVM, MS (From Arboretum View Speciality Services, 2551 Warrenville Rd., Downers Grove, IL 60515)


Summary: Seven cats with thyroid carcinomas that had previously undergone surgical removal of neoplastic tissue were treated with 30 mCi of radioactive iodine (131I). Six of the cats had clinical signs of hyperthyroidism (1); did not. There were no complications associated with 131I treatment, and clinical signs resolved in all cats. Technetium scans of 4 cats made after treatment did not have evidence of isotope uptake. In the remaining 3 cats, small areas of isotope uptake, the intensity of which was equal to or less than the intensity of uptake in the salivary glands, were seen. All 7 cats became hypothyroid after treatment (4); required L-thyroxine supplementation. One cat was alive 33 months after treatment. The other 6 cats were euthanatized because of unrelated diseases 10 to 41 months after treatment.


[View Abstract-PubMed]  Published in the Journal of American Veterinary Medicine Association (JAVMA), Vol. 207, No. 8, October 15, 1995, Scientific Reports.


 

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