Toxin from tobacco smoke could increase pain in spinal cord injury and worsen multiple sclerosis

Dec 3, 2014

A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period.

Purdue startup commercializing innovation to reduce neurotoxin that damages nerve cells, triggers pain

Sep 26, 2014

A Purdue startup is commercializing a technology that could reduce the symptoms and pain of neurological disease and injury, including multiple sclerosis, neuropathic pain and Parkinson's disease.

Neuro Vigor licenses innovative Purdue technology to treat neurological diseases

Apr 24, 2014

Neuro Vigor LLC announced Thursday (April 24) the signing of an exclusive worldwide license with Purdue Research Foundation to develop and commercialize technology that promises an innovative approach to reducing the symptoms and pain of neurological disease and injury, including multiple sclerosis, neuropathic pain and Parkinson's disease.

Drug may reduce chronic pain for spinal cord injuries

Oct 29, 2013

Researchers have discovered that a known neurotoxin may cause chronic pain in people who suffer from paralysis, and a drug that has been shown to remove the toxin might be used to treat the pain.

Testing promising for spinal cord injuries, multiple sclerosis

Jun 13, 2013

A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms.

Study gets major boost to probe toxin's role in spinal injury, potential treatment

Feb 14, 2012

Researchers, led by Dr. Riyi Shi, have received $1.5 million to study the role of a toxin thought to worsen the severity of spinal cord injuries and to learn whether reducing its concentration in the days following trauma also decreases damage that can lead to paralysis.

Purdue Research Foundation reception to honor university entrepreneurs, researchers

November 1, 2011

Fifty-nine Purdue University faculty, staff and students whose discoveries received patents during the 2010-2011 fiscal year will be recognized Wednesday (Nov. 2) during the Purdue Research Foundation's annual Inventors Recognition Reception.

Purdue research may lead to therapy that delays onset, reduces severity of MS symptoms

March 14, 2011

Purdue professor Riyi Shi conducts research at his laboratory on how hydralazine affects multiple sclerosis symptoms. A provisional patent has ...

Purdue Research Foundation recognizes university researchers, entrepreneurs

November 4, 2010

Riyi Shi, professor, Weldon School of Biomedical Engineering, College of Engineering; professor, Department of Basic Medical Sciences, ...

Drug studied as possible treatment for spinal injuries

November 19, 2009

Researchers have shown how an experimental drug might restore the function of nerves damaged in spinal cord injuries by preventing short circuits caused when tiny "potassium channels" in the fibers are exposed. ...

Findings show nanomedicine promising for treating spinal cord injuries

November 8, 2009

The collaboration included Borgens; Riyi Shi, an associate professor of biomedical engineering and basic medical sciences; and Kinam Park, ...

Spun-sugar fibers spawn sweet technique for nerve repair

February 26, 2009

Riyi Shi, Weldon School of Biomedical Engineering ... in nerves, said Riyi Shi, an associate professor in Purdue's Weldon School of Biomedical ...

'CARS' imaging reveals clues to myelin damage

June 27, 2007

Researchers have discovered that calcium ions could play a crucial role in multiple sclerosis by activating enzymes that degrade the fatty sheath that insulates nerve fibers.